Karlsruhe airfield was built on the parade ground of a barracks area in the northwest of the city. After the First World War, the field was initially closed before it was reopened in the mid-1920s as a commercial airfield and integrated into the air traffic network. At that time, the airport's facilities were located in the south-western corner of the site.
From the mid-1930s onwards, the airport was expanded, the movement area was extended to the north and airfield facilities were built on the east side. A flight school of the Nationalsozialistischen Fliegerkorps (NSFK) was established at the field. In World War II, the airfield was occupied by individual units.
At the end of World War II, the airfield was occupied by US troops. Later, the US Army takes over and used it with individual aircraft and helicopters. In 1993 the site was closed and the US Army withdrew completely until 1995. Today the airport is a nature reserve.